Healthcare AI owns the market now. Traditional models die.
Digital health funding hit $6.4 billion in H1 2025. Most went to AI startups. They raise bigger rounds. Exit faster.
The old playbook failed. But healthcare isn't dead. Drug discovery accelerated. Value-based care works. IPOs returned.
This guide lists 35 active healthcare investors. What they want. How to reach them.
Track your healthcare pitch deck
Clinical trial data validates. FDA pathway mapped. Enterprise pilots signed.
Yet investors don't respond.
Static PDFs fail. Track engagement instead. See which slides capture attention.
Ellty helps healthcare startups understand investor behavior.
35 Top healthcare investors
1. OrbiMed Advisors
World's largest dedicated healthcare investor with $17 billion AUM.
Investment focus: Therapeutics, diagnostics, devices, services across all stages
Investment range: Seed to public markets, $5M-$500M+
Notable investments: Sarepta, SAGE Therapeutics, BioNTech
Contact: orbimed.com
2. ARCH Venture Partners
Pioneer in company creation and transformative healthcare investments.
Investment focus: Biotech, synthetic biology, cell therapy, computational drug discovery
Investment range: Seed to late stage, often leads creation rounds
Notable investments: Illumina, Juno Therapeutics, Grail
Contact: archventure.com
3. RA Capital Management
Evidence-based healthcare investor with integrated research platform.
Investment focus: Public and private healthcare across all subsectors
Investment range: $10M-$500M+, crossover specialist
Notable investments: 100+ healthcare companies, TechAtlas platform
Contact: racap.com
4. Deerfield Management
$12 billion healthcare investment firm with operational platform.
Investment focus: Life sciences, medical technology, healthcare services
Investment range: Venture to buyout, $10M-$1B+
Notable investments: 3DC drug development platform, Cure campus
Contact: deerfield.com
5. MPM Capital (MPM BioImpact)
Company-building healthcare investor since 1993.
Investment focus: Therapeutics across all modalities, company creation
Investment range: Seed to growth, $5M-$100M+
Notable investments: Aktis Oncology, Orna Therapeutics, Life Edit
Contact: mpmbioimpact.com
6. Versant Ventures
Leading healthcare VC with discovery engine model.
Investment focus: Biotech, medical devices, healthcare IT
Investment range: Company creation to growth
Notable investments: 100+ companies, multiple IPOs
Contact: versantventures.com
7. 5AM Ventures
Life sciences specialist investing at dawn of innovation.
Investment focus: Biotech, research tools, diagnostics
Investment range: Seed to Series B, $5M-$50M
Notable investments: Denali Therapeutics, Audentes
Contact: 5amventures.com
8. Venrock
Healthcare pioneer since backing Intel and Apple, now focused on healthcare.
Investment focus: Healthcare IT, services, therapeutics, devices
Investment range: Seed to growth
Notable investments: Illumina, Athenahealth, Personal Genome Diagnostics
Contact: venrock.com
9. SV Health Investors (formerly SV Life Sciences)
Global healthcare investor across therapeutics and services.
Investment focus: Biotech venture, healthcare services growth equity
Investment range: Early to late stage, $10M-$200M+
Notable investments: 100+ healthcare companies globally
Contact: svhealthinvestors.com
10. General Catalyst
Technology investor with major healthcare practice.
Investment focus: Digital health transformation, health IT
Investment range: Seed to growth, $1M-$200M+
Notable investments: Livongo, Mindstrong, Color
Contact: generalcatalyst.com
11. B Capital
Global firm with dedicated healthcare strategy.
Investment focus: Healthtech, biotech, medtech, digital health
Investment range: Series A to growth, $10M-$100M+
Notable investments: 40+ healthcare companies, 5 IPOs
Contact: bcapgroup.com
12. Norwest Venture Partners
Diversified investor with strong healthcare practice.
Investment focus: Healthcare services, devices, digital health
Investment range: Early to late stage, $5M-$100M+
Notable investments: Karius, Progyny, Talis Biomedical
Contact: nvp.com
13. Rock Health
First dedicated digital health venture fund.
Investment focus: Digital health exclusively
Investment range: Seed to Series A, $500K-$5M
Notable investments: Omada Health, Collective Health
Contact: rockhealth.com
14. Optum Ventures
Strategic healthcare investor by UnitedHealth Group.
Investment focus: Healthcare services, technology, care delivery
Investment range: Series A to growth, $5M-$50M+
Notable investments: 75+ portfolio companies, $2B+ AUM
Contact: optumventures.com
15. Healthy Ventures
Seed stage digital health specialist.
Investment focus: Digital health technologies
Investment range: Seed, $500K-$2M
Notable investments: Marley Medical, Turquoise Health
Contact: healthy.vc
16. 7wire Ventures
Healthcare consumer-focused investor.
Investment focus: Informed connected health consumer
Investment range: Early stage, $2M-$15M
Notable investments: Healthcare consumer platforms
Contact: 7wireventures.com
17. a16z Bio + Health
Andreessen Horowitz's dedicated healthcare fund.
Investment focus: Bio, health services, software in healthcare
Investment range: Seed to growth, $1M-$100M+
Notable investments: Pearl Health, Devoted Health
Contact: a16z.com/bio-health
18. Polaris Partners
Healthcare and technology investor since 1972.
Investment focus: Healthcare and technology convergence
Investment range: Early to growth stage
Notable investments: 100+ healthcare companies
Contact: polarispartners.com
19. New Enterprise Associates (NEA)
One of world's largest VCs with major healthcare practice.
Investment focus: Healthcare services, devices, IT, therapeutics
Investment range: Seed to growth, $1M-$200M+
Notable investments: 200+ healthcare companies
Contact: nea.com
20. Third Rock Ventures
Company-building life sciences investor.
Investment focus: Biotech company creation
Investment range: Company formation to growth
Notable investments: 70+ companies launched
Contact: thirdrockventures.com
21. Atlas Venture
Biotech-focused early stage investor.
Investment focus: Therapeutics company building
Investment range: Seed to Series B, $5M-$50M
Notable investments: 90+ biotech companies
Contact: atlasventure.com
22. Canaan
Early stage investor with healthcare focus.
Investment focus: Digital health, devices, services
Investment range: Seed to Series B
Notable investments: Healthcare technology leaders
Contact: canaan.com
23. Insight Partners
Software investor with healthcare vertical.
Investment focus: Healthcare software, data platforms
Investment range: Series B+, $10M-$500M+
Notable investments: Healthcare IT leaders
Contact: insightpartners.com
24. ShangBay Capital
Medtech specialist based in Silicon Valley.
Investment focus: Medical devices, diagnostics
Investment range: Series A to C, $5M-$30M
Notable investments: Ceribell, 72+ portfolio companies
Contact: shangbaycapital.com
25. TPG Healthcare
Private equity healthcare platform.
Investment focus: Healthcare services, value-based care
Investment range: Growth equity to buyout, $50M-$1B+
Notable investments: ArchWell Health, Monogram Health
Contact: tpg.com
26. Summit Partners
Growth equity investor in healthcare.
Investment focus: Healthcare services, tech-enabled care
Investment range: $25M-$500M+
Notable investments: $2.7B+ in healthcare deals
Contact: summitpartners.com
27. Leerink Partners
Healthcare-focused investment bank with venture arm.
Investment focus: All healthcare subsectors
Investment range: Various stages
Notable investments: Healthcare leaders across sectors
Contact: leerink.com
28. Longitude Capital
Healthcare growth equity specialist.
Investment focus: Healthcare companies at inflection points
Investment range: $25M-$150M
Notable investments: 50+ healthcare companies
Contact: longitudecapital.com
29. Sofinnova Partners
European life sciences investor.
Investment focus: Biotech, medtech, digital health
Investment range: Seed to late stage
Notable investments: 500+ companies over 50 years
Contact: sofinnovapartners.com
30. Abingworth
Transatlantic life sciences investor.
Investment focus: Therapeutics, medtech, diagnostics
Investment range: Early to late stage
Notable investments: International healthcare leaders
Contact: abingworth.com
31. F-Prime Capital
Healthcare and technology investor by Fidelity.
Investment focus: Healthcare IT, services, therapeutics
Investment range: Early to growth stage
Notable investments: Healthcare transformation companies
Contact: fprimecapital.com
32. Maverick Capital
Hedge fund with venture healthcare arm.
Investment focus: Healthcare technology, services
Investment range: Growth stage, $20M+
Notable investments: Digital health leaders
Contact: maverickcapital.com
33. Warburg Pincus
Global PE with major healthcare practice.
Investment focus: Healthcare services, pharma services
Investment range: $100M-$1B+
Notable investments: Large healthcare platforms
Contact: warburgpincus.com
34. Oak HC/FT
Healthcare and fintech specialist.
Investment focus: Healthcare services, IT, tech-enabled services
Investment range: Early to growth, $5M-$100M+
Notable investments: Healthcare technology leaders
Contact: oakhcft.com
35. Frazier Healthcare Partners
Dedicated healthcare growth investor.
Investment focus: Healthcare services, life sciences
Investment range: Growth equity, $20M-$200M+
Notable investments: 170+ healthcare investments
Contact: frazierhealthcare.com
How to approach healthcare investors
What matters in healthcare
Healthcare investors evaluate differently than other sectors.
Clinical evidence trumps everything. Have data or a clear path to it.
Regulatory strategy must be detailed. FDA pathway, reimbursement codes, compliance framework.
Team credentials matter more. MD/PhD founders get meetings. Industry veterans close deals.
The diligence deep dive
Prepare for scrutiny:
- Clinical trial design review
- Regulatory consultant calls
- Physician KOL references
- Reimbursement pathway analysis
- Competitive clinical data comparison
Healthcare diligence takes 3-6 months. Start preparing early.
Getting warm introductions
Portfolio company CEOs make best intros. Find investors' healthcare portfolios. Connect with founders.
Medical advisors open doors. KOLs in your specialty know investors.
Healthcare conferences work. JPM Healthcare Conference, BIO, specialized summits.
Alternative funding sources
Government programs
SBIR/STTR: NIH alone has $1.2B annually for small business R&D
BARDA: Funds advanced development for public health threats
DoD medical: Military medical innovation funding
State programs: Many states have life science funding
Strategic investors
Pharma ventures: J&J Innovation, Novartis Venture Fund, Roche Ventures
Device strategics: Medtronic Ventures, BD Ventures, Boston Scientific Ventures
Payer innovation: Blues venture funds, Humana Ventures
Foundations and nonprofits
Disease foundations often fund early research. Gates Foundation for global health. Patient advocacy groups for rare diseases.
Success stories
Recent mega-rounds
Hinge Health: Digital MSK preparing IPO after $400M+ raised
Devoted Health: Medicare Advantage reaching $12.6B valuation
Insitro: ML drug discovery raised $400M Series C
Exits driving the market
One Medical: Amazon acquisition for $3.9B validated primary care
Signify Health: CVS bought for $8B, proved value-based care model
Biohaven: Pfizer acquisition for $11.6B showed biotech exits remain strong
Why healthcare startups fail
Underestimated regulatory timeline. FDA delayed 18 months. Ran out of cash.
Reimbursement strategy failed. Great product, no one pays.
Clinical trial missed endpoint. $50M spent, back to preclinical.
How Ellty helps healthcare startups
Healthcare pitch decks require depth. Clinical data gets scrutinized. Regulatory slides studied longest.
Ellty shows you:
- Which investors spend time on clinical data
- When scientific advisors review your deck
- Who forwards to healthcare partners
Healthcare founders report:
- 2.5x response rate with tracking
- Know which VCs have medical partners
- Identify who understands your therapeutic area
FAQs
Q: How much runway for healthcare startup?
24-36 months minimum. Clinical and regulatory timelines are unpredictable.
Q: When to raise for FDA trials?
Raise 6 months before IND filing. Trial costs upfront.
Q: Do I need healthcare-specific investors?
For Series A+, yes. Seed can be generalist.
Q: How important is IP in healthcare?
Critical for therapeutics. Less for services. Varies by model.
Q: Should we hire regulatory consultants early?
Yes. Investors want to see regulatory strategy from day one.
